Class 12 Chemistry · Chapter 9 · Test 3
Retrosynthesis and Drug Design
46 MCQs
46 questions · 40 min · 46 marks
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Sample questions
The first 5 of 46. Try each one, then tap to see the answer.
Question 1
After disconnection the components obtained are called:
- ATarget molecule
- BSynthons
- CSynthetic equivalents
- DStarting material
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Answer: B
Fragments generated by a disconnection are called synthons.
Question 2
How will you convert the amide functional group to the amine group?
- ABy an oxidation reaction
- BBy a reduction reaction
- CBy an acid hydrolysis
- DBy an addition reaction
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Answer: B
LiAlH4 reduces an amide to an amine.
Question 3
What does the open-ended arrow (⇒) mean in organic chemistry?
- ASynthesis
- BRetrosynthesis
- CReversible reaction
- DDisconnection
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Answer: B
It is the retrosynthetic arrow.
Question 4
Which reagent will you choose to convert an aldehyde group into an alcohol?
- AKMnO4/H+
- BNaBH4/H3O+
- CZn/HCl
- DNa/liquid NH3
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Answer: B
NaBH4 reduces aldehydes to primary alcohols.
Question 5
Which reagent is commonly used to oxidise a primary alcohol into a carboxylic acid?
- APCC
- BLiAlH4
- CAcidified K2Cr2O7
- DNaBH4
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Answer: C
Acidified dichromate under reflux gives the acid; PCC stops at the aldehyde and the others are reducing agents.
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